Products No. Hopeland 111

Product Name: Phytase Producing Technology and Equipment

Equipment Picture

1. Flow Chart as below

1. First grade seed
2. The second grade seed
3. The third grade seed
4. Ferment tank
5. Ferment process
6. Producing process section
7. Micro-filtration to remove the bacterium
8. Airflow drying
9. Decolour
10. Embalmment
11. Ultrafiltration concentration
12. Spray drying
13. Extrusion granulator
14. Swaying granulator
15. Pill core
16. Fine Micro-filtration
17. Swaying granulator
18. Coating
19. Product compose section
20. Liquid typical product
21. High active enzyme pure white product
22. Coated product
23. Granular product
24. Powder product

2. Ferment technique (60MT)

Ferment flow is belonged to typical Pichia pastoris semicontinuous fermentation, it contains 3 phases.

a)Seed phase
Generally, Seed phase has two kinds shaking bottle, 500L ferment tank seed, 6Ton ferment tank seed.

b)Thalli accumulating phase
In 60 tank, thalli use up all the carbon source and supplement carbon source, thalli reaches a some concentration.

c)Abduction phase
In the condiction of methanol FED-BATCH, the thalli is abducted to produce Phytate,and gradually accumulate.
Main equipment: fermentation tank,material storage tank, Air Compressor, boiler and auto-control equipment.

3. Producing Technology and Equipment Arrangement

a)Powder production Technology
Powder product is made by spray drying or airflow drying method. The proportion,color and quality of the powder made by spray drying is better.
Basic technique: ferment liquid acquire clear liquid through Flat-frame filtration or Ceramic membrane filtration. You may usethe ferment liquid directly, then mix it, then spray drying, and then separate the rough powder, fine power and residue by sifter.
Main equipment: ferment liquid storage tank, filtration equipment(optional), spray dryer or airflow dryer.

b)Granular production technique
Grain products can be made by mixing, swaying, cast pill, drying and sifting process.
Basic technique: sprayed powder is mixed through stated proportion and carrier and excipient, and then enter to swaying granulator to make the granulate. At last, separate them by sifting equipment.
Main equipment: mixer, swaying granulator, abrator, multi-function granulator, sifting equipment.

c)Coated enzyme production technique
Coated product can be made by extrusion granulating,cast pill,drying,coating, and sifting process.
Basic technique: sprayed powder is mixed through a certainty proportionand carrier and excipien. And then enter extrusion granulator, and then goes to the Abrator to make pill, then enter the boiling dryer granulator to obtain a pill core, pill core is coated in the coating machine, then separate by sifter.
Main equipment: mixer, extrusion granulator, Abrator, multi-funtion granulator(with coating function), sifting equipment.

d)Liquid enzyme production technique
Liquid typical enzyme technique mainly includes bacterium removing and producing process.
Basic technique: axenic ferment liquid can be made trough flat-frame Filtration, centrifugal machine or Ceramic membrane filtration. And then conpound the product in the tank under a certain formulation. At last to remove the impurity through Ceramic membrane filtration system to gain the ready product.
Main equipment: centrifugal machine or flat –frame Filtration machine, Ceramic membrane filtration system, producing tank, , ready products storage tank and so on.

For more information please contact us: 85xianji@85xianji.com and icec0529@yahoo.com